Coating with flexible DNA network enhanced T-cell activation and tumor killing for adoptive cell therapy

• Main Authors: Ziyan Zhang (Author), Qiaojuan Liu (Author), Jizhou Tan (Author), Xiaoxia Zhan (Author), Ting Liu (Author), Yuting Wang (Author), Gen Lu (Author), Minhao Wu (Author), Yuanqing Zhang (Author)
• Format: Book
• Published: Elsevier, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adoptive cell therapy (ACT) is an emerging powerful cancer immunotherapy, which includes a complex process of genetic modification, stimulation and expansion. During these in vitro or ex vivo manipulation, sensitive cells are inescapability subjected to harmful external stimuli. Although a variety o...