LC-MS-Based Metabolomic Study of Oleanolic Acid-Induced Hepatotoxicity in Mice

• Main Authors: Hong Feng (Author), Ying-Qiu Wu (Author), Ya-Sha Xu (Author), Ke-Xin Wang (Author), Xue-Mei Qin (Author), Yuan-Fu Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oleanolic acid (OA), a natural triterpenoid, which has the development prospects in anti-tumor therapy is a widely used hepatoprotective drug in China. It has been reported that OA can cause liver toxicity after higher doses or longer-term use. Therefore, the study aims to explore the possible hepat...