Polymorphic Variants of TNFR2 Gene in Schizophrenia and Its Interaction with -308G/A TNF-α Gene Polymorphism

• Main Authors: Renata Suchanek-Raif (Author), Paweł Raif (Author), Małgorzata Kowalczyk (Author), Monika Paul-Samojedny (Author), Krzysztof Kucia (Author), Wojciech Merk (Author), Jan Kowalski (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim. Many data showed a role of inflammation and dysfunction of immune system as important factors in the risk of schizophrenia. The TNFR2 receptor is a molecule that adapts to both areas. Tumor necrosis factor receptor 2 (TNFR2) is a receptor for the TNF-α cytokine which is a strong candidate gene...