PACAP attenuates hepatic lipid accumulation through the FAIM/AMPK/IRβ axis during overnutrition

• Main Authors: Wei Luo (Author), Jiaxin Dai (Author), Jianmin Liu (Author), Yongmei Huang (Author), Ziqiong Zheng (Author), Pei Xu (Author), Yi Ma (Author)
• Format: Book
• Published: Elsevier, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Pituitary adenylate cyclase-activating polypeptide (PACAP) was reported to attenuate hepatic lipid accumulation in overnutrition-related metabolic disorder, mediated by up-regulation of fas apoptosis inhibitory molecule (FAIM). However, how PACAP regulates FAIM in metabolic tissues remain...