Neutrophil-mediated delivery of pixantrone-loaded liposomes decorated with poly(sialic acid)-octadecylamine conjugate for lung cancer treatment

• Main Authors: Xiang Luo (Author), Ling Hu (Author), Huangliang Zheng (Author), Mingqi Liu (Author), Xinrong Liu (Author), Cong Li (Author), Qiujun Qiu (Author), Zitong Zhao (Author), Xiaobo Cheng (Author), Chaoyang Lai (Author), Yuqing Su (Author), Yihui Deng (Author), Yanzhi Song (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Poly(sialic acid) (PSA) is a natural hydrophilic biodegradable and non-immunogenic biopolymer, receptors for its monomer are expressed on peripheral blood neutrophils (PBNs), which plays important roles in the progression and invasion of tumors. A poly(sialic acid)-octadecylamine conjugate (PSA-ODA)...