Recombinant human insulin-like growth factor-1 promotes osteoclast formation and accelerates orthodontic tooth movement in rats

• Main Authors: Ju-Xiang Peng (Author), Xiao-Yan Guan (Author), Gao-Hua Li (Author), Jian-Li Zhong (Author), Ju-Kun Song (Author), Lin-Lin Xiao (Author), Su-Han Jin (Author), Jian-Guo Liu (Author)
• Format: Book
• Published: University of São Paulo, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background: IGF-1 may be an important factor in bone remodeling, but its mechanism of action on osteoclasts during orthodontic tooth movement is complex and unclear. Methodology: The closed-coil spring was placed between the left maxillary first molar and upper incisors with a force of 50 g...