Therapeutic Dosage of Antipsychotic Drug Aripiprazole Induces Persistent Mitochondrial Hyperpolarisation, Moderate Oxidative Stress in Liver Cells, and Haemolysis

• Hoofdauteurs: Tinkara Pirc Marolt (Auteur), Barbara Kramar (Auteur), Andrej Vovk (Auteur), Helena Podgornik (Auteur), Dušan Šuput (Auteur), Irina Milisav (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Aripiprazole has fewer metabolic side effects than other antipsychotics; however, there are some severe ones in the liver, leading to drug-induced liver injury. Repeated treatment with aripiprazole affects cell division. Since this process requires a lot of energy, we decided to investigate the impa...