Differentiation of adult human retinal pigment epithelial cells into dopaminergic-like cells in vitro and in the recipient monkey brain

• Main Authors: Sha Li (Author), Han Zhang (Author), Aifang Wang (Author), Yan Liu (Author), Houqi Liu (Author), Feng Yue (Author), Xianmixinuer Abulaiti (Author), Caiqiao Zhang (Author), Lingsong Li (Author)
• Format: Book
• Published: BMC, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cell therapy is proposed to be a potential treatment for Parkinson's disease (PD). Although fetal retinal pigment epithelial (RPE) cells have been tested in trials for treating PD patients, controversy has been raised over the issue of whether such cells can be reprogrammed...