Four Weeks of Treatment With Rifaximin Fails to Significantly Alter Microbial Diversity in Rectal Samples of HIV-Infected Immune Non-Responders (ACTG A5286) Which May be Attributed to Rectal Swab Use

• Main Authors: Brett B. Williams (Author), Stefan J. Green (Author), Ronald J. Bosch (Author), Ellen S. Chan (Author), Jeffrey M. Jacobson (Author), David M. Margolis (Author), Phillip Engen (Author), Alan L. Landay (Author), Cara C. Wilson (Author)
• Format: Book
• Published: Case Western Reserve University, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: HIV-infected individuals have evidence of intestinal microbial translocation which is associated with immune activation and unfavorable clinical outcomes. Rifaximin, a non-absorbable antibiotic which reduces microbial translocation in other disease states, was shown to have a marginal...