Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/ PPARα-NF-κB/IR-S2 signaling pathway

• Main Authors: Doha Reda (Author), Gehad E. Elshopakey (Author), Talat A. Albukhari (Author), Samah J. Almehmadi (Author), Bassem Refaat (Author), Engy F. Risha (Author), Hebatallah A. Mahgoub (Author), Mohamed E. El-Boshy (Author), Fatma M. Abdelhamid (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Nonalcoholic fatty liver disease (NAFLD) is a chronic disease characterized by fat deposits in liver cells, which can lead to hepatitis and fibrosis. This study attempted to explore the protective effect of vitamin D3 (VitD) against NAFLD.Methods: Adult male albino rats were randomized...