Discovery of a small-molecule NDR1 agonist for prostate cancer therapy

• Main Authors: Yang Bai (Author), Xiuyuan Sui (Author), Zuodong Xuan (Author), Yifan Du (Author), Meiling Fu (Author), Zeyuan Zheng (Author), Kunao Yang (Author), Chunlan Xu (Author), Yankuo Liu (Author), Bin Liu (Author), Min Zhong (Author), Zhengying Zhang (Author), Jianzhong Zheng (Author), Xiaoyan Hu (Author), Lei Zhang (Author), Huimin Sun (Author), Chen Shao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prostatic cancer (PCa) is a common malignant neoplasm in men worldwide. Most patients develop castration-resistant prostate cancer (CRPC) after treatment with androgen deprivation therapy (ADT), usually resulting in death. Therefore, investigating new therapeutic targets and drugs for PCa patients i...