ZWZ-3, a Fluorescent Probe Targeting Mitochondria for Melanoma Imaging and Therapy

• Main Authors: Zengjin Liu (Author), Hailan Wang (Author), Changzhen Sun (Author), Yuanmin He (Author), Tong Xia (Author), Jianv Wang (Author), Xia Xiong (Author), Qingbi Zhang (Author), Sijin Yang (Author), Li Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The increased drug resistance and metastasis of melanoma resulted in poor prognosis of patients. Here, we designed and synthesized a novel hemicyanine-based fluorescent probe ZWZ-3, and investigated its application for melanoma imaging and treatment both in vitro and in vivo. ZWZ-3 preferentially ac...