Mouse Idh3a mutations cause retinal degeneration and reduced mitochondrial function
Isocitrate dehydrogenase (IDH) is an enzyme required for the production of α-ketoglutarate from isocitrate. IDH3 generates the NADH used in the mitochondria for ATP production, and is a tetramer made up of two α, one β and one γ subunit. Loss-of-function and missense mutations in both IDH3A and IDH3...
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Formato: | Libro |
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The Company of Biologists,
2018-12-01T00:00:00Z.
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Número de Clasificación: |
A1234.567 |
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Copia 1 | Dispoñible |