Astragalus membranaceus and its monomers treat peritoneal fibrosis and related muscle atrophy through the AR/TGF-β1 pathway

• Автори: Li Sheng (Автор), Jinyi Sun (Автор), Liyan Huang (Автор), Manshu Yu (Автор), Xiaohui Meng (Автор), Yun Shan (Автор), Huibo Dai (Автор), Funing Wang (Автор), Jun Shi (Автор), Meixiao Sheng (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: To anticipate the potential molecular mechanism of Astragalus membranaceus (AM) and its monomer, Calycosin, against peritoneal fibrosis (PF) and related muscle atrophy using mRNA-seq, network pharmacology, and serum pharmacochemistry.Methods: Animal tissues were examined to evaluate a CK...