Astragalus membranaceus and its monomers treat peritoneal fibrosis and related muscle atrophy through the AR/TGF-β1 pathway

• Main Authors: Li Sheng (Author), Jinyi Sun (Author), Liyan Huang (Author), Manshu Yu (Author), Xiaohui Meng (Author), Yun Shan (Author), Huibo Dai (Author), Funing Wang (Author), Jun Shi (Author), Meixiao Sheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: To anticipate the potential molecular mechanism of Astragalus membranaceus (AM) and its monomer, Calycosin, against peritoneal fibrosis (PF) and related muscle atrophy using mRNA-seq, network pharmacology, and serum pharmacochemistry.Methods: Animal tissues were examined to evaluate a CK...