Treadmill Training Increases SIRT-1 and PGC-1α Protein Levels and AMPK Phosphorylation in Quadriceps of Middle-Aged Rats in an Intensity-Dependent Manner

• Main Authors: Nara R. C. Oliveira (Author), Scherolin O. Marques (Author), Thais F. Luciano (Author), José R. Pauli (Author), Leandro P. Moura (Author), Erico Caperuto (Author), Bruno L. S. Pieri (Author), Julia Engelmann (Author), Gisele Scaini (Author), Emilio L. Streck (Author), Fabio S. Lira (Author), Ricardo A. Pinho (Author), Eduardo R. Ropelle (Author), Adelino S. R. Silva (Author), Cláudio T. De Souza (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study investigated the effects of running at 0.8 or 1.2 km/h on inflammatory proteins (i.e., protein levels of TNF-α, IL-1β, and NF-κB) and metabolic proteins (i.e., protein levels of SIRT-1 and PGC-1α, and AMPK phosphorylation) in quadriceps of rats. Male Wistar rats at 3 (young) and 18...