Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends

• Auteurs principaux: Kenza Abouir (Auteur), Caroline F Samer (Auteur), Yvonne Gloor (Auteur), Jules A Desmeules (Auteur), Youssef Daali (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Physiologically-based pharmacokinetics (PBPK) modeling is a robust tool that supports drug development and the pharmaceutical industry and regulatory authorities. Implementation of predictive systems in the clinics is more than ever a reality, resulting in a surge of interest for PBPK models by clin...