Free circulating ICAM-1 in serum and cerebrospinal fluid of HIV-1 infected patients correlate with TNF-α and blood-brain barrier damage

• Main Authors: M. K. Sharief (Author), M. Ciardi (Author), M. A. Noori (Author), E. J. Thompson (Author), A. Salotti (Author), F. Sorice (Author), F. Rossi (Author), A. Cirelli (Author)
• Format: Book
• Published: Hindawi Limited, 1992-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The mechanism for the initiation of blood-brain barrier damage and intrathecal inflammation in patients infected with the human immunodeficiency virus (HIV) is poorly understood. We have recently reported that tumour necrosis factor-α (TNF-α) mediates active neural inflammation and blood-brain barri...