History of the G Protein-Coupled Receptor (GPCR) Assays From Traditional to a State-of-the-Art Biosensor Assay

• Main Authors: Kanako Miyano (Author), Yuka Sudo (Author), Akinobu Yokoyama (Author), Kazue Hisaoka-Nakashima (Author), Norimitsu Morioka (Author), Minoru Takebayashi (Author), Yoshihiro Nakata (Author), Yoshikazu Higami (Author), Yasuhito Uezono (Author)
• Format: Book
• Published: Elsevier, 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: The G protein-coupled receptors (GPCRs) form the largest and the most versatile superfamily that share a seven-transmembrane-spanning architecture. GPCR-signaling is involved in vision, taste, olfaction, sympathetic/parasympathetic nervous functions, metabolism, and immune regulation, ind...