Cholesterol improves the transfection efficiency of polyallylamine as a non-viral gene delivery vector

• Glavni autori: Reza Kazemi Oskuee (Autor), Mahdieh Ramezanpour (Autor), Leila Gholami (Autor), Bizhan Malaekeh-Nikouei (Autor)
• Format: Knjiga
• Izdano: Universidade de São Paulo, 2017-10-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

ABSTRACT Cationic polymers such as polyallylamine (PAA) having primary amino groups are poor transfection agents and possess a high cytotoxicity index when used without any chemical modification. In this study, PAA was modified with cholesterol in order to improve transfection efficiency and to redu...