The Inhibition of LPS-Induced Oxidative Stress and Inflammatory Responses Is Associated with the Protective Effect of (-)-Epigallocatechin-3-Gallate on Bovine Hepatocytes and Murine Liver

• Egile Nagusiak: Tianle Xu (Egilea), Run Liu (Egilea), Hao Zhu (Egilea), Yu Zhou (Egilea), Tianxu Pei (Egilea), Zhangping Yang (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

This study aimed to evaluate whether (-)-epigallocatechin-3-gallate (EGCG) alleviates hepatic responses to lipopolysaccharide (LPS)-induced inflammation and oxidation. Isolated bovine hepatocytes and BALB/c mice were used for LPS challenge and EGCG pretreatment experiments in vitro and in vivo. LPS-...