Transient Receptor Potential Ankyrin-1 (TRPA1) Block Protects against Loss of White Matter Function during Ischaemia in the Mouse Optic Nerve

• Main Authors: Wendy Lajoso (Author), Grace Flower (Author), Vincenzo Giacco (Author), Anjuli Kaul (Author), Circe La Mache (Author), Andra Brăban (Author), Angela Roxas (Author), Nicola B. Hamilton (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oligodendrocytes produce myelin, which provides insulation to axons and speeds up neuronal transmission. In ischaemic conditions, myelin is damaged, resulting in mental and physical disabilities. Recent evidence suggests that oligodendrocyte damage during ischaemia can be mediated by Transient Recep...