Physicochemical characterisation of spray dried ternary solid dispersions of simvastatin. Processability, tableting and dissolution
Simvastatin(SMV) is poorly soluble drug classified as belonging to Class II of Biopharmaceutics Classification System. Common approach to improve apparent solubility of drugs is production of amorphous solid dispersions (ASD) by means of spray drying(SD) or hot-melt extrusion. Spray drying of low-gl...
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University of Huddersfield Press,
2019-04-01T00:00:00Z.
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