Physicochemical characterisation of spray dried ternary solid dispersions of simvastatin. Processability, tableting and dissolution

Simvastatin(SMV) is poorly soluble drug classified as belonging to Class II of Biopharmaceutics Classification System. Common approach to improve apparent solubility of drugs is production of amorphous solid dispersions (ASD) by means of spray drying(SD) or hot-melt extrusion. Spray drying of low-gl...

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Main Authors: Hanan Abdalmaula (Author), Anant Paradkar (Author), Krzysztof J Paluch (Author)
Format: Book
Published: University of Huddersfield Press, 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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