Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates

• मुख्य लेखकों: Yuta Suzuki (लेखक), Takayuki Miyazaki (लेखक), Hiroki Muto (लेखक), Kenji Kubara (लेखक), Yohei Mukai (लेखक), Ryuji Watari (लेखक), Shinya Sato (लेखक), Keita Kondo (लेखक), Shin-ichi Tsukumo (लेखक), Koji Yasutomo (लेखक), Masashi Ito (लेखक), Kappei Tsukahara (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

mRNA and lipid nanoparticles have emerged as powerful systems for the preparation of vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The emergence of novel variants or the necessity of cold chain logistics for approved mRNA vaccines undermines the investigati...