Substantially Increased Plasma Coproporphyrin‐I Concentrations Associated With OATP1B1*15 Allele in Japanese General Population

• Main Authors: Yosuke Suzuki (Author), Yuri Sasamoto (Author), Teruhide Koyama (Author), Chisato Yoshijima (Author), Masahiro Nakatochi (Author), Michiaki Kubo (Author), Yukihide Momozawa (Author), Ritei Uehara (Author), Keiko Ohno (Author)
• Format: Book
• Published: Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Coproporphyrin‐I (CP‐I) in plasma is a sensitive and specific endogenous probe for phenotyping organic anion transporting polypeptides 1B (OATP1B, encoded by SLCO1B). A few small‐scale studies suggested that plasma CP‐I concentration is affected by OATP1B1 polymorphism, but detailed studies are lack...