Design, synthesis, and screening of ortho-amino thiophene carboxamide derivatives on hepatocellular carcinomaas VEGFR-2Inhibitors

In this work, design, synthesis, and screening of thiophene carboxamides 4-13 and 16-23 as dual vascular endothelial growth factor receptors (VEGFRs) and mitotic inhibitors was reported. All compounds were screened against two gastrointestinal solid cancer cells, HepG-2 and HCT-116 cell lines. The m...

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Main Authors: Mohammed K. AbdElhameid (Author), Madlen B. Labib (Author), Ahmed T. Negmeldin (Author), Muhammad Al-Shorbagy (Author), Manal R. Mohammed (Author)
Format: Book
Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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