Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy

• Main Authors: Melanie Gartz (Author), Chien-Wei Lin (Author), Mark A. Sussman (Author), Michael W. Lawlor (Author), Jennifer L. Strande (Author)
• Format: Book
• Published: The Company of Biologists, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiomyopathy is a leading cause of early mortality in Duchenne muscular dystrophy (DMD). There is a need to gain a better understanding of the molecular pathogenesis for the development effective therapies. Exosomes (exo) are secreted vesicles and exert effects via their RNA, lipid and protein car...