Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium: a randomized, exploratory, open-label trial.

• Main Authors: Jennifer Keiser (Author), Kigbafori D Silué (Author), Lukas K Adiossan (Author), Nicaise A N'Guessan (Author), N'Chou Monsan (Author), Jürg Utzinger (Author), Eliézer K N'Goran (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis. The antimalarial drug mefloquine shows antischistosomal activity in animal models and clinical trials, which calls for...