Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms.

• Main Authors: Yan Hu (Author), Bin Zhan (Author), Brian Keegan (Author), Ying Y Yiu (Author), Melanie M Miller (Author), Kathryn Jones (Author), Raffi V Aroian (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hookworm infections are one of the most important parasitic infections of humans worldwide, considered by some second only to malaria in associated disease burden. Single-dose mass drug administration for soil-transmitted helminths, including hookworms, relies primarily on albendazole, which has var...