Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms.

• Hoofdauteurs: Yan Hu (Auteur), Bin Zhan (Auteur), Brian Keegan (Auteur), Ying Y Yiu (Auteur), Melanie M Miller (Auteur), Kathryn Jones (Auteur), Raffi V Aroian (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Hookworm infections are one of the most important parasitic infections of humans worldwide, considered by some second only to malaria in associated disease burden. Single-dose mass drug administration for soil-transmitted helminths, including hookworms, relies primarily on albendazole, which has var...