Microglia activation in a pediatric rabbit model of tuberculous meningitis

• Main Authors: Elizabeth W. Tucker (Author), Supriya Pokkali (Author), Zhi Zhang (Author), Vincent P. DeMarco (Author), Mariah Klunk (Author), Elizabeth S. Smith (Author), Alvaro A. Ordonez (Author), Marie-France Penet (Author), Zaver Bhujwalla (Author), Sanjay K. Jain (Author), Sujatha Kannan (Author)
• Format: Book
• Published: The Company of Biologists, 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Central nervous system (CNS) tuberculosis (TB) is the most severe form of extra-pulmonary TB and disproportionately affects young children where the developing brain has a unique host response. New Zealand white rabbits were infected with Mycobacterium tuberculosis via subarachnoid inoculation at po...