Cortisol Exerts bi-phasic Regulation of Inflammation in Humans

• Hauptverfasser: Mark P. Yeager MD (Verfasst von), Patricia A. Pioli PhD (Verfasst von), Paul M. Guyre PhD (Verfasst von)
• Format: Buch
• Veröffentlicht: SAGE Publishing, 2011-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Natural and synthetic glucocorticoids (GCs) have been used for decades to suppress inflammation. In this paper, we re-examine the role of the endogenous GC, cortisol, as a primary homeostatic regulator of the human inflammatory response to injury. Our data show that cortisol regulation of innate imm...