PLGA and PDMS-based in situ forming implants loaded with rosuvastatin and copper-selenium nanoparticles: a promising dual-effect formulation with augmented antimicrobial and cytotoxic activity in breast cancer cells

• Главные авторы: Amr Maged (Автор), Mostafa Mabrouk (Автор), Hanzada T. Nour El-Din (Автор), Lamyaa Osama (Автор), Shaimaa M. Badr-Eldin (Автор), Azza A. Mahmoud (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Предметы: article
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Breast cancer is among the most prevalent tumors worldwide. In this study, in-situ forming implants (ISFIs) containing rosuvastatin calcium were prepared using three types of poly (D, L-lactic-co-glycolic acid) (PLGA), namely, PLGA 50/50 with ester terminal and PLGA 75/25 with ester or acid terminal...