Metabolomic Analysis by Nuclear Magnetic Resonance Spectroscopy as a New Approach to Understanding Inflammation and Monitoring of Pharmacological Therapy in Children and Young Adults With Cystic Fibrosis

• Main Authors: Paolo Montuschi (Author), Vincenzina Lucidi (Author), Debora Paris (Author), Enza Montemitro (Author), Rugia Shohreh (Author), Nadia Mores (Author), Dominique Melck (Author), Giuseppe Santini (Author), Fabio Majo (Author), Andrea Motta (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

15-F2t-Isoprostane, a reliable biomarker of oxidative stress, has been found elevated in exhaled breath condensate (EBC), a non-invasive technique for sampling of airway secretions, in patients with cystic fibrosis (CF). Azithromycin has antioxidant properties in experimental models of CF, but its e...