Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior

• Главные авторы: M. Leo (Автор), M. Schulte (Автор), L.-I. Schmitt (Автор), M. Schäfers (Автор), C. Kleinschnitz (Автор), T. Hagenacker (Автор)
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• Опубликовано: Hindawi Limited, 2017-01-01T00:00:00Z.
• Предметы: article
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Transient receptor potential vanilloid-1 (TRPV1) is a nonselective cation channel, predominantly expressed in sensory neurons. TRPV1 is known to play an important role in the pathogenesis of inflammatory and neuropathic pain states. Previous studies suggest interactions between tumor necrosis factor...