A network paradigm predicts drug synergistic effects using downstream protein-protein interactions
Abstract In some cases, drug combinations affect adverse outcome phenotypes by binding the same protein; however, drug‐binding proteins are associated through protein-protein interaction (PPI) networks within the cell, suggesting that drug phenotypes may result from long‐range network effects. We fi...
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Format: | Book |
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Wiley,
2022-11-01T00:00:00Z.
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A1234.567 |
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