miRNAs 144-3p, 34a-5p, and 206 are a useful signature for distinguishing uterine leiomyosarcoma from other smooth muscle tumors

• Main Authors: Beatriz Nunes Schiavon (Author), Katia Candido Carvalho (Author), Cláudia Malheiros Coutinho-Camillo (Author), Glauco Baiocchi (Author), Renan Valieris (Author), Rodrigo Drummond (Author), Israel Tojal da Silva (Author), Louise De Brot (Author), Fernando Augusto Soares (Author), Isabela Werneck da Cunha (Author)
• Format: Book
• Published: BMC, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Leiomyosarcoma (LMS) is a rare uterine neoplasm that has a high mortality rate and no specific treatment. The origin of LMS remains unknown; although, it is hypothesized that LMS arises from the malignant transformation of a degenerated uterine leiomyoma (LM). LMs are the most co...