Clinical Experience with Off-Label Intrathecal Administration of Selected Antibiotics in Adults: An Overview with Pharmacometric Considerations

• मुख्य लेखकों: Anouk E. Muller (लेखक), Peter van Vliet (लेखक), Birgit C. P. Koch (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Drain-associated intracerebral infections are life-threatening emergencies. Their treatment is challenging due to the limited penetration of antibiotics to the site of infection, resulting in potentially inadequate exposure. The emergence of multidrug-resistant pathogens might force the use of off-l...