A high throughput neutralization test based on GFP expression by recombinant rabies virus.

• Main Authors: Jillybeth Burgado (Author), Lauren Greenberg (Author), Mike Niezgoda (Author), Amrita Kumar (Author), Victoria Olson (Author), Xianfu Wu (Author), Panayampalli Subbian Satheshkumar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The effectiveness of rabies vaccination in both humans and animals is determined by the presence of virus neutralizing antibodies (VNAs). The Rapid Fluorescent Focus Inhibition Test (RFFIT) is the method traditionally used for detection and quantification of VNAs. It is a functional in vitro test fo...