Contributive Role of TNF-α to L-DOPA-Induced Dyskinesia in a Unilateral 6-OHDA Lesion Model of Parkinson's Disease

• Päätekijät: Maurício dos Santos Pereira (Tekijä), Gabriel Henrique Dias Abreu (Tekijä), Jeremy Rocca (Tekijä), Sabah Hamadat (Tekijä), Rita Raisman-Vozari (Tekijä), Patrick Pierre Michel (Tekijä), Elaine Del Bel (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Our present objective was to better characterize the mechanisms that regulate striatal neuroinflammation in mice developing L-DOPA-induced dyskinesia (LID). For that, we used 6-hydroxydopamine (6-OHDA)-lesioned mice rendered dyskinetic by repeated intraperitoneal injections of 3,4-dihydroxyphenyl-L-...