Targeting the eCIRP/TREM-1 interaction with a small molecule inhibitor improves cardiac dysfunction in neonatal sepsis

Abstract Background Neonatal sepsis and the associated myocardial dysfunction remain a leading cause of infant mortality. Extracellular cold-inducible RNA-binding protein (eCIRP) acts as a ligand of triggering receptor expressed on myeloid cells-1 (TREM-1). M3 is a small CIRP-derived peptide that in...

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Main Authors: Naomi-Liza Denning (Author), Monowar Aziz (Author), Li Diao (Author), Jose M. Prince (Author), Ping Wang (Author)
Format: Book
Published: BMC, 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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