Edaravone-loaded poly(amino acid) nanogel inhibits ferroptosis for neuroprotection in cerebral ischemia injury

• Main Authors: Yunhan Zhang (Author), Zhulin Zou (Author), Shuang Liu (Author), Fangfang Chen (Author), Minglu Li (Author), Haoyang Zou (Author), Haiyan Liu (Author), Jianxun Ding (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurological injury caused by ischemic stroke is a major cause of permanent disability and death. The currently available neuroprotective drugs fail to achieve desired therapeutic efficacy mainly due to short circulation half-life and poor blood−brain barrier (BBB) permeability. For that, an edaravo...