Determination of Extravasation Effects of Nal-Iri and Trabectedin and Evaluation of Treatment Options for Trabectedin Extravasation in a Preclinical Animal Model

• Main Authors: Omar Keritam (Author), Viktoria Juhasz (Author), Christian Schöfer (Author), Christiane Thallinger (Author), Marie-Bernadette Aretin (Author), Gernot Schabbauer (Author), Johannes Breuss (Author), Matthias Unseld (Author), Pavel Uhrin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Extravasation during chemotherapy administration can lead to dangerous adverse effects ranging from pain to tissue necrosis. Evidence-based data about prevention and treatment of extravasation injuries of some clinically used compounds still remains elusive. This work aimed to investigat...