Physicochemical, thermodynamic and analytical studies on binary and ternary inclusion complexes of bosentan with hydroxypropyl-β-cyclodextrin
The interactions of poorly aqueous soluble endothelin receptor antagonist bosentan (BOS) with hydroxypropyl-β-cyclodextrin (HPβCD) were assessed in presence and absence of an amino acid l-arginine (ARG), to improve its physicochemical properties. Initially, the phase solubility studies conducted in...
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Format: | Book |
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Faculty of Pharmacy, Cairo University,
2017-06-01T00:00:00Z.
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A1234.567 |
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