Effect of Genetic and Nongenetic Factors on the Clinical Response to Mineralocorticoid Receptor Antagonist Therapy in Egyptians with Heart Failure

• Main Authors: Neven M. Sarhan (Author), Mohamed H. Shahin (Author), Nihal M. El Rouby (Author), Lamia M. El‐Wakeel (Author), Mohamed H. Solayman (Author), Taimour Langaee (Author), Hazem Khorshid (Author), Mona F. Schaalan (Author), Nagwa A. Sabri (Author), Larisa H. Cavallari (Author)
• Formato: Livro
• Publicado em: Wiley, 2020-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

This prospective cohort study evaluated the association between the renin angiotensin aldosterone system genotypes and response to spironolactone in 155 Egyptian patients with heart failure with reduced ejection fraction (HFrEF). Genotype frequencies for AGT rs699 were: CC = 16%, CT = 48%, and TT = ...