Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus
Genetic gain-of-function mutations of warm temperature-sensitive transient receptor potential vanilloid 3 (TRPV3) channel cause Olmsted syndrome characterized by severe itching and keratoderma, indicating that pharmacological inhibition of TRPV3 may hold promise for therapy of chronic pruritus and s...
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Main Authors: | Hang Qi (Author), Yuntao Shi (Author), Han Wu (Author), Canyang Niu (Author), Xiaoying Sun (Author), KeWei Wang (Author) |
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Format: | Book |
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Elsevier,
2022-02-01T00:00:00Z.
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