Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway

• Main Authors: Yiyang Wang (Author), Baoshuai Bai (Author), Yanzhu Hu (Author), Haoming Wang (Author), Ningyuan Liu (Author), Yibo Li (Author), Pei Li (Author), Guangdong Zhou (Author), Qiang Zhou (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Established studies proved that hydrostatic pressure had multiple effects on the biological behavior of the intervertebral disc (IVD). However, the conclusions of the previous studies were inconsistent, due to the difference in hydrostatic loading devices and observing methods used in these studies....