Assessing developability early in the discovery process for novel biologics

• Main Authors: Monica L. Fernández-Quintero (Author), Anne Ljungars (Author), Franz Waibl (Author), Victor Greiff (Author), Jan Terje Andersen (Author), Torleif T. Gjølberg (Author), Timothy P. Jenkins (Author), Bjørn Gunnar Voldborg (Author), Lise Marie Grav (Author), Sandeep Kumar (Author), Guy Georges (Author), Hubert Kettenberger (Author), Klaus R. Liedl (Author), Peter M. Tessier (Author), John McCafferty (Author), Andreas H. Laustsen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTBeyond potency, a good developability profile is a key attribute of a biological drug. Selecting and screening for such attributes early in the drug development process can save resources and avoid costly late-stage failures. Here, we review some of the most important developability properti...