Increased Abundance of Plasmacytoid Dendritic Cells and Interferon-Alpha Induces Plasma Cell Differentiation in Patients of IgA Nephropathy

• প্রধান লেখক: Nuoyan Zheng (লেখক), Bing Wang (লেখক), Jinjin Fan (লেখক), Ning Luo (লেখক), Qingyu Kong (লেখক), Hongjian Ye (লেখক), Jiqin Zhang (লেখক), Hongyan Ming (লেখক), Xueqing Yu (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Hindawi Limited, 2017-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The roles of pDC and IFN-α have not been well defined in IgA nephropathy (IgAN). In this study, we investigated the abundance of pDCs and IFN-α in IgAN patients and the response of peripheral blood mononuclear cells (PBMCs) after stimulation of the pDC-preferred TLR9 ligand CpG2216. The effects of I...