Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity

• Những tác giả chính: Dalia Ali (Tác giả), Elna P. Chalisserry (Tác giả), Muthurangan Manikandan (Tác giả), Rimi Hamam (Tác giả), Musaad Alfayez (Tác giả), Moustapha Kassem (Tác giả), Abdullah Aldahmash (Tác giả), Nehad M. Alajez (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2018-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Bone marrow mesenchymal stem cells (BMSCs) are adult multipotent stem cells that can differentiate into mesodermal lineage cells, including adipocytes and osteoblasts. However, the epigenetic mechanisms governing the lineage-specific commitment of BMSCs into adipocytes or osteoblasts are under inves...