Extracellular vesicle microRNA and protein cargo profiling in three clinical-grade stem cell products reveals key functional pathways

• Main Authors: Ramana Vaka (Author), Sandrine Parent (Author), Yousef Risha (Author), Saad Khan (Author), David Courtman (Author), Duncan J. Stewart (Author), Darryl R. Davis (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cell origin-specific payloads within extracellular vesicles (EVs) mediate therapeutic bioactivity for a wide variety of stem cell types. In this study, we profiled the microRNA (miRNA) and protein cargos found within EVs produced by three clinical-grade stem cell products of different ontogenies...