Important Lessons on Long-Term Stability of Amino Acids in Stored Dried Blood Spots

• Main Authors: Allysa M. Dijkstra (Author), Pim de Blaauw (Author), Willemijn J. van Rijt (Author), Hanneke Renting (Author), Ronald G. H. J. Maatman (Author), Francjan J. van Spronsen (Author), Rose E. Maase (Author), Peter C. J. I. Schielen (Author), Terry G. J. Derks (Author), M. Rebecca Heiner-Fokkema (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Residual heel prick Dried Blood Spots (DBS) are valuable samples for retrospective investigation of inborn metabolic diseases (IMD) and biomarker analyses. Because many metabolites suffer time-dependent decay, we investigated the five-year stability of amino acids (AA) in residual heel prick DBS. In...